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Herpes Simplex Virus Type 1 Infection Imposes a G1/S Block in Asynchronously Growing Cells and Prevents G1 Entry in Quiescent Cells

✍ Scribed by Ginger L. Ehmann; Tim I. McLean; Steven L. Bachenheimer


Book ID
112272429
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
335 KB
Volume
267
Category
Article
ISSN
0042-6822

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## Abstract Skin fibroblasts exposed to cytosine arabinoside (Ara C) were infected with either cytomegalovirus (CMV) or herpes simplex virus (HSV) type 1 and 2. Herpesvirus‐determined early antigens (HV‐EA), detected by anti‐complement immunofluorescence (ACIF), occurred primarily in the nuclei, an