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Herpes simplex virus type-1 can reactivate transcription of latent human immunodeficiency virus

✍ Scribed by Mosca, J. D.; Bednarik, D. P.; Raj, N. B. K.; Rosen, C. A.; Sodroski, J. G.; Haseltine, W. A.; Pitha, P. M.

Book ID
109747959
Publisher
Nature Publishing Group
Year
1987
Tongue
English
Weight
496 KB
Volume
325
Category
Article
ISSN
0028-0836

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It was proposed recently that CEM CD4-positive T cells infected chronically by herpes simplex virus type 1 (HSV-1) and human immunodeficiency virus type 1 (HIV-1) (CEM(HSV/HIV)) may be used as a model for studying HIV/HSV interactions. To ascertain whether HSV-HIV coinfection of T lymphocytes has a