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HERPES SIMPLEX VIRUS INFECTION AND APOPTOSIS

✍ Scribed by GOODKIN, MARGOT. L.; MORTON, ELISE. R.; BLAHO, JOHN. A.


Book ID
111975689
Publisher
Informa plc
Year
2004
Tongue
English
Weight
487 KB
Volume
23
Category
Article
ISSN
0883-0185

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Frontline: Induction of apoptosis and mo
✍ Dagmar B. MΓΌller; Martin J. Raftery; Angela Kather; Thomas Giese; GΓΌnther SchΓΆnr πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 291 KB

## Abstract Herpes simplex virus (HSV) can perturb the function of dendritic cells (DC). The underlying mechanisms are not defined. In the present study we demonstrate that HSV induces a substantial number of immature DC to undergo apoptosis by a mechanism involving caspase‐8. We found strongly enh