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Heritability of factors of the insulin resistance syndrome in women twins

โœ Scribed by Karen L. Edwards; Beth Newman; Elizabeth Mayer; Joe V. Selby; Ronald M. Krauss; Melissa A. Austin

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
45 KB
Volume
14
Category
Article
ISSN
0741-0395

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โœฆ Synopsis

P > 0.05), and 0.71 (P < 0.001), respectively. The insulin/glucose factor appeared to be highly heritable, with estimates of 0.87, 0.92, and 0.57 (all P < 0.001), respectively. The heritability estimates for the lipid factor were moderate and consistent across methods: 0.25 (P < 0.10), 0.32 (P < 0.05), and 0.30 (P < 0.05), respectively. These results are consistent with genetic influences on each of the 3 "factors," and suggest that both genetic and environmental effects are involved in the clustering of IRS risk factors. Genet. Epidemiol. 14:241-253, 1997.

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