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Hereditary renal cell carcinoma in the Eker rat: a unique animal model for the study of cancer susceptibility

โœ Scribed by Jeffrey I. Everitt; Thomas L. Goldsworthy; Douglas C. Wolf; Cheryl L. Walker


Book ID
118411920
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
545 KB
Volume
82-83
Category
Article
ISSN
0378-4274

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๐Ÿ“œ SIMILAR VOLUMES


Uterine leiomyoma in the Eker rat: A uni
โœ Cheryl Lyn Walker; Deborah Hunter; Jeffery I. Everitt ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 175 KB

## Abstract Eker rats carry a defect in the __Tscโ€2__ tumor suppressor gene and female Eker rats develop uterine leiomyoma with a high frequency. The presentation, response to hormones and molecular alterations in these mesenchymal smooth muscle tumors, closely resembles their cognate human disease