A s of 1999, it is possible to test selected subjects for carriage of germline mutations in genes responsible for familial adenomatous polyposis (FAP), 1,2 hereditary nonpolyposis colorectal cancer (HNPCC), 3,4 Peutz-Jeghers syndrome, 5 and juvenile polyposis. 6,7 These diseases are heterogeneous ph
Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). I. Clinical description of resource
โ Scribed by Henry T. Lynch; William Kimberling; William A. Albano; Jane F. Lynch; Karen Biscone; Guy S. Schuelke; Avery A. Sandberg; Martin Lipkin; Eleanor E. Deschner; Yves B. Mikol; Robert C. Elston; Joan E. Bailey-Wilson; B. Shannon Danes
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 463 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Hereditary nonpolyposis colorectal carcinoma (HNPCC) is the most common hereditary form of colorectal carcinoma (CRC) and may account for 5-10% of the total CRC burden. The discovery of DNA mismatch repair (MMR) genes, inclusive of hMSH2, hMLH1, hPMS2, and hMSH6, has enabled the identification of wh
Hereditary cancer represents approximately 5-10% of the total cancer burden and may account for 60,000 to 120,000 new cancer occurrences this year in the United States. New developments in molecular genetics and the cloning of cancer-prone genes have intensely fueled interest in dealing with heredit