๐”– Bobbio Scriptorium
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Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). I. Clinical description of resource

โœ Scribed by Henry T. Lynch; William Kimberling; William A. Albano; Jane F. Lynch; Karen Biscone; Guy S. Schuelke; Avery A. Sandberg; Martin Lipkin; Eleanor E. Deschner; Yves B. Mikol; Robert C. Elston; Joan E. Bailey-Wilson; B. Shannon Danes


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
463 KB
Volume
56
Category
Article
ISSN
0008-543X

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โœ Patrick M. Lynch ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 107 KB ๐Ÿ‘ 1 views

A s of 1999, it is possible to test selected subjects for carriage of germline mutations in genes responsible for familial adenomatous polyposis (FAP), 1,2 hereditary nonpolyposis colorectal cancer (HNPCC), 3,4 Peutz-Jeghers syndrome, 5 and juvenile polyposis. 6,7 These diseases are heterogeneous ph

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โœ Henry T. Lynch; Patrice Watson; Trudy G. Shaw; Jane F. Lynch; Anne E. Harty; Bar ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 114 KB ๐Ÿ‘ 2 views

Hereditary nonpolyposis colorectal carcinoma (HNPCC) is the most common hereditary form of colorectal carcinoma (CRC) and may account for 5-10% of the total CRC burden. The discovery of DNA mismatch repair (MMR) genes, inclusive of hMSH2, hMLH1, hPMS2, and hMSH6, has enabled the identification of wh

Clinical impact of molecular genetic dia
โœ Henry T. Lynch; Patrice Watson; Trudy G. Shaw; Jane F. Lynch; Anne E. Harty; Bar ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 164 KB ๐Ÿ‘ 2 views

Hereditary cancer represents approximately 5-10% of the total cancer burden and may account for 60,000 to 120,000 new cancer occurrences this year in the United States. New developments in molecular genetics and the cloning of cancer-prone genes have intensely fueled interest in dealing with heredit