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Hereditary Non-Syndromic Sensorineural Hearing Loss

✍ Scribed by Schrijver, Iris


Book ID
121089252
Publisher
American Society for Investigative Pathology
Year
2004
Tongue
English
Weight
167 KB
Volume
6
Category
Article
ISSN
1525-1578

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Hereditary hearing loss (HHL) is an extremely common disorder. About 70% of HHL is non-syndromic, with autosomal recessive forms accounting for ~ 85% of the genetic load. Although very heterogeneous, the most common cause of HHL in many different world populations is mutations of GJB2, a gene that e