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Hereditary diffuse gastric cancer: lifesaving potential of prophylactic gastrectomy

✍ Scribed by Aparna Mukherjee; Thomas McGarrity; Kevin Staveley-O'Carroll; Francesca Ruggiero; Maria J. Baker

Book ID
118628103
Publisher
Frontline Medical Communications, Inc.
Year
2009
Tongue
English
Weight
151 KB
Volume
6
Category
Article
ISSN
1548-5315

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Hereditary diffuse gastric cancer : Diag
Hereditary diffuse gastric cancer : Diagnosis, genetic counseling, and prophylactic total gastrectomy
✍ Henry T. Lynch; Pardeep Kaurah; Debrah Wirtzfeld; Wendy S. Rubinstein; Scott Wei πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 685 KB

## Abstract ## BACKGROUND. A subset of patients with diffuse gastric cancer harbor deleterious cancer‐causing germline mutations in the type 1 E‐cadherin (epithelial) gene (__CDH1__), which predisposes to the autosomal dominantly inherited hereditary diffuse gastric cancer (HDGC) syndrome. These m