Hereditary causes of chorea in childhood
β Scribed by Katherine D. Mathews
- Book ID
- 114353476
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 943 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1071-9091
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Snmmerp: Benign hereditary chorea (BHC) is an autosomal dominant disorder characterized by chorea of early onset with little or no progression. There is marked clinical variability in this disease with some subjects having onset in infancy and others with onset in early adulthood. In contrast to Hun
## Abstract Benign hereditary chorea (BHC) recently has been associated with mutations in TITFβ1 gene, although a pathological study of an individual with BHC and a TITFβ1 mutation revealed no significant gross or microscopic abnormalities using standard methods. Immunohistochemical staining of str