Novel transthyretin missense mutation (T
โ
Patrosso, M. Cristina; Salvi, Fabrizio; De Grandis, Domenico; Vezzoni, Paolo; Ja
๐
Article
๐
1998
๐
John Wiley and Sons
๐
English
โ 11 KB
๐ 2 views
We report on the genetic and molecular characterisation of an Italian family with a late-onset, autosomal dominant transthyretin amyloidosis. The transthyretin gene was analysed by polymerase chain reaction (PCR), restriction generating PCR, and sequencing, allowing us to discover in one allele a no