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Hereditary Ataxia in the Jack Russell Terrier– Clinical and Genetic Investigations

✍ Scribed by Annette Wessmann; Thomas Goedde; Andrea Fischer; Peter Wohlsein; Henning Hamann; Ottmar Distl; Andrea Tipold


Book ID
118094130
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
75 KB
Volume
18
Category
Article
ISSN
0891-6640

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Clinical and genetic findings in Finnish
✍ Vesa Juvonen; Marja Hietala; Markku Päivärinta; Maria Rantamäki; Lauri Hakamies; 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 352 KB 👁 1 views

Spinocerebellar ataxia 8 (SCA8) is caused by a CTG repeat expansion in an untranslated region of a recently cloned gene on 13q21. The pathogenic role of this trinucleotide repeat was evaluated by examining 154 Finnish ataxia patients and 448 controls. Expansions ranging from 100 to 675 repeats were