✦ LIBER ✦

Herbal products for liver diseases: A therapeutic challenge for the new millennium

✍ Scribed by Detlef Schuppan; Ji-Dong Jia; Benno Brinkhaus; Eckhart G. Hahn

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 76 KB
Volume: 30
Category: Article
ISSN: 0270-9139
DOI: 10.1002/hep.510300437

No coin nor oath required. For personal study only.

✦ Synopsis

Use of herbal drugs in the treatment of liver diseases has a long tradition, especially in Eastern medicine. Standardization has been a problem, and randomized, placebo-controlled clinical trials to support efficacy are lacking. Some herbal extracts promoted for gastrointestinal or biliary disorders contain potent hepatotoxic alkaloids and are harmful. However, some of these extracts have yielded molecules, often related to flavonoids, with proven antioxidative, antifibrotic, antiviral, or anticarcinogenic properties, including glycyrrhizin, phyllanthin, silibinin, picroside, and baicalein, which derive from licorice root, Phyllanthus amarus, milk thistle, Picrorhiza kurroa, and sho-saiko-to, respectively, that can serve as primary compounds for the development of specific hepatotropic drugs.

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