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Herb-drug interactions: Focus on metabolic enzymes and transporters

✍ Scribed by Young Hee Choi; Young-Won Chin; Yoon Gyoon Kim

Book ID
107642578
Publisher
Springer
Year
2011
Tongue
English
Weight
548 KB
Volume
34
Category
Article
ISSN
0253-6269

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✍ Matthew D. Merrell; Lisa M. Augustine; Angela L. Slitt; Nathan J. Cherrington 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 325 KB

## Abstract Coordinate regulation of Phase‐I and ‐II enzymes with xenobiotic transporters has been shown after treatment with microsomal enzyme inducers. The chemopreventive agent oltipraz (OPZ) induces Phase‐I and ‐II drug‐metabolizing enzymes such as CYP2B and NQO1. The purpose of this study was