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HER2gene status in primary breast cancers and matched distant metastases

✍ Scribed by Coya Tapia, Spasenija Savic, Urs Wagner, René Schönegg…

Book ID
120700324
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
332 KB
Volume
9
Category
Article
ISSN
1465-5411

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## Abstract ## BACKGROUND. The Akt/mammalian target of the rapamycin (mTOR) signaling pathway represents a promising target for cancer therapy. The phosphorylation status of Akt and of mTOR's phosphorylation target eukaryotic initiation factor 4E‐binding protein 1 (4E‐BP1) is often used to assess