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HER2 shedding and serum HER2 extracellular domain: Biology and clinical utility in breast cancer

✍ Scribed by Chantal Tsé; Anne-Sophie Gauchez; William Jacot; Pierre-Jean Lamy

Book ID
116395564
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
319 KB
Volume
38
Category
Article
ISSN
0305-7372

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## Abstract The question of the serum HER2 extracellular domain (HER2/ECD) measurement for prediction of response to the anti‐HER2 antibody Trastuzumab is still an open and current matter of clinical debate. To elucidate the involvement of shed HER2/ECD in HER2‐driven tumor progression and in guidi