HER2 protein expression and HER2 gene amplification are infrequent in small intestinal carcinomas
โ Scribed by Mi Jin Gu, Seung-Mo Hong, Soo Jin Jung
- Book ID
- 120905480
- Publisher
- Springer
- Year
- 2013
- Tongue
- English
- Weight
- 236 KB
- Volume
- 462
- Category
- Article
- ISSN
- 1432-2307
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
HER2 is an erbB/HER type 1 tyrosine kinase receptor that is frequently over-expressed in malignant epithelial tumours. Herceptin, a humanised mouse monoclonal antibody to HER2, is proven therapeutically in the management of metastatic breast cancer, significantly prolonging survival when combined wi
## Abstract HER 2/__neu__ is an important oncogene in breast cancer, but the prevalence and significance of HER 2/__neu__ gene amplification in colon cancer have been poorly documented. We have evaluated HER 2/__neu__ gene amplification and protein overexpression in a series of colon cancers to ass