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HER2 mRNA Status Contributes to the Discrepancy Between Gene Amplification and Protein Overexpression in Gastric Cancer

✍ Scribed by Ma, Gui-Fen; Liu, Yi-Mei; Gao, Hong; Miao, Qing; Luo, Tian-Cheng; Zeng, Xiao-Qing; Chen, Shi-Yao

Book ID: 121551560
Publisher: Springer US
Year: 2013
Tongue: English
Weight: 562 KB
Volume: 59
Category: Article
ISSN: 0163-2116
DOI: 10.1007/s10620-013-2925-1

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## Abstract The __HER2__ oncogene, which encodes the tyrosine kinase receptor, is commonly overexpressed in several types of cancer. Treatment using a humanized monoclonal antibody bound to __HER2__ product is becoming standard therapy for advanced breast cancer. Overexpression occurs in approximat