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HER-2 Gene Amplification, HER-2 and Epidermal Growth Factor Receptor mRNA and Protein Expression, and Lapatinib Efficacy in Women with Metastatic Breast Cancer

✍ Scribed by Press, M. F.; Finn, R. S.; Cameron, D.; Di Leo, A.; Geyer, C. E.; Villalobos, I. E.; Santiago, A.; Guzman, R.; Gasparyan, A.; Ma, Y.; Danenberg, K.; Martin, A. M.; Williams, L.; Oliva, C.; Stein, S.; Gagnon, R.; Arbushites, M.; Koehler, M. T.


Book ID
125525872
Publisher
American Association for Cancer Research
Year
2008
Tongue
English
Weight
570 KB
Volume
14
Category
Article
ISSN
1078-0432

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## Abstract ## BACKGROUND. Epidermal growth factor receptor (EGFR, HER‐1, and __erbB__1) is overexpressed in primary breast cancer and had been identified as a poor prognostic factor. ## METHODS. Pretreatment serum EGFR levels were quantified by using an enzyme‐linked immunoadsorbent assay in a