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Hepcidin is a key mediator of anemia of inflammation in Crohn's disease

โœ Scribed by Basseri, Robert J.; Nemeth, Elizabeta; Vassilaki, Maria E.; Basseri, Benjamin; Enayati, Pedram; Shaye, Omid; Bourikas, Leonidas A.; Ganz, Tom; Papadakis, Konstantinos A.

Book ID
122577325
Publisher
Oxford University Press
Year
2013
Tongue
English
Weight
524 KB
Volume
7
Category
Article
ISSN
1873-9946

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## Inflammation influences iron balance in the whole organism. A common clinical manifestation of these changes is anemia of chronic disease (ACD; also called anemia of inflammation). Inflammation reduces duodenal iron absorption and increases macrophage iron retention, resulting in low serum iron c