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Hepcidin and iron-related gene expression in subjects with Dysmetabolic Hepatic Iron Overload

✍ Scribed by Donatella Barisani; Sara Pelucchi; Raffaella Mariani; Stefania Galimberti; Paola Trombini; Daniela Fumagalli; Raffaella Meneveri; Elizabeta Nemeth; Tomas Ganz; Alberto Piperno


Book ID
116651587
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
294 KB
Volume
49
Category
Article
ISSN
0168-8278

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Ferroportin disease (hemochromatosis type 4) is a recently recognized disorder of human iron metabolism, characterized by iron deposition in macrophages, including Kupffer cells. Mutations in the gene encoding ferroportin 1, a cellular iron exporter, are responsible for this iron storage disease, in