Alcohol reduces and iron increases liver hepcidin synthesis. This study investigates the interaction of alcohol and iron in the regulation of hepcidin messenger RNA (mRNA) expression in animal models. Mice were administered 10% ethanol for 7 days after an iron-overloaded diet. Rats were administered
Hepcidin and iron-mediated resistance to malaria
โ Scribed by Andrew M. Prentice
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 523 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1757-4676
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Strain variation in the level of resistance to malaria was investigated in inbred mice after infection with Plasmodium chabaudi. Following intraperitoneal infection with the typing dose of parasitized erythrocytes, mice of 11 inbred strains could be separated using survival time as the criterium int
Hepcidin, a recently discovered iron regulatory peptide, is believed to inhibit the release of iron from absorptive enterocytes and macrophages. Liver hepcidin synthesis is induced in vivo by iron stores and inflammation. The molecular basis of the regulation of hepcidin gene expression by these eff