𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hepatotoxicity of the herbal medicine germander: Metabolic activation of its furano diterpenoids by cytochrome P450 3A Depletes cytoskeleton-associated protein thiols and forms plasma membrane blebs in rat hepatocytes

✍ Scribed by M Lekehal; D Pessayre; JM Lereau; C Moulis; I Fourasté; D Fau

Book ID
118686361
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
267 KB
Volume
24
Category
Article
ISSN
0270-9139

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Hepatotoxicity of the herbal medicine ge
Hepatotoxicity of the herbal medicine germander: Metabolic activation of its furano diterpenoids by cytochrome P450 3A Depletes cytoskeleton-associated protein thiols and forms plasma membrane blebs in rat hepatocytes
✍ M Lekehal; D Pessayre; J M Lereau; C Moulis; I Fourasté; D Fau 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 275 KB 👁 2 views

Several herbal remedies have produced hepatitis in humans. The medicinal plant, germander, was recalled after its use as an adjuvant to slimming diets resulted in an epidemic of hepatitis in France. We studied the hepatotoxicity of germander in isolated rat hepatocytes. A crude fraction containing t