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Hepatotoxic Activity of Semi-Synthetic Analogues of Pyrrolizidine Alkaloids

✍ Scribed by SCHOENTAL, R.; MATTOCKS, A. R.

Book ID
109607227
Publisher
Nature Publishing Group
Year
1960
Tongue
English
Weight
295 KB
Volume
185
Category
Article
ISSN
0028-0836

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πŸ“œ SIMILAR VOLUMES

Dihydropyrrolizine analogues of pyrroliz
Dihydropyrrolizine analogues of pyrrolizidine alkaloids
✍ C.C.J. Culvenor; J.A. Edgar; L.W. Smith; H.J. Tweeddale πŸ“‚ Article πŸ“… 1969 πŸ› Elsevier Science 🌐 French βš– 222 KB

The dihydropyrrolizine analogues (I) of the hepatotoxic pyrrolizidine alkaloids have been suggested as possible toxic metabolites of the alkaloids (1,2,3). The formation of Ehrlich-positive metabolites has been demonstrated (2,4) and the major metabolite of this type formed in the rat from heliotrin