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Hepatoprotective activity of chitosan against isoniazid and rifampicin-induced toxicity in experimental rats

โœ Scribed by Sethumadhavan Santhosh; Theruvathil K. Sini; Rangasamy Anandan; Paruthapara T. Mathew

Book ID
113587003
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
204 KB
Volume
572
Category
Article
ISSN
0014-2999

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Picroliv, the active constituent of the plant Picrorhiza Kurroa, showed significant hepatoprotective as well as anticholestatic activity against rifampicin-induced hepatic damage. Rifampicin (50 mg/kg ip ร— 6 days) resulted in the reduction of bile flow as well as its contents (bile salts and bile ac