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Hepatocytic TGFβ1 is involved in interferon alfa-2B (IFN)-induced apoptosis on rat preneoplastic liver

✍ Scribed by M.L. Alvarez; M.T. Ronco; J. Monti; J.E. Ochoa; C. Carnovale; G. Pisani; M.C. Lugano; M.C. Carrillo

Book ID
117372293
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
164 KB
Volume
38
Category
Article
ISSN
0168-8278

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Interferon α-induced apoptosis on rat preneoplastic liver is mediated by hepatocytic transforming growth factor β1
✍ María de Luján Alvarez; María Teresa Ronco; J. Elena Ochoa; Juan A. Monti; Crist 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 324 KB

In previous work we showed that interferon alfa-2b (IFN-alpha2b) increases apoptosis on rat hepatic preneoplastic foci. The aim of this study was to determine if transforming growth factor beta1 (TGF-beta1) was involved in the programmed cell death on the foci. Animals were divided into 6 groups: su