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Hepatocyte growth factor in fulminant hepatic failure

✍ Scribed by Robin D. Hughes; Christopher D. Gove; Roger Williams; Hirohita Tsubouchi; Yasushi Daikuhara

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
248 KB
Volume
11
Category
Article
ISSN
0270-9139

No coin nor oath required. For personal study only.

✦ Synopsis

We read with great interest the paper by Tsubouchi et al. (1) on the hepatocyte growth factor (hHGF) in the blood of patients with fulminant hepatic failure (FHF). These authors have already elegantly reported the purification and partial characterization of hHGF from the plasma of a patient with FHF (2).

The current paper reports the stimulatory effects of 5% FHF serum on 3H-thymidine incorporation in cultured rat hepatocytes. These results could be caused by many substances in serum, including hHGF. It is in-

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