Human hepatocyte growth factor (hHGF), which is now known to be the same protein as the scatter factor and the tumor cytotoxic factor, is a heterodimeric protein with one heavy chain and one light chain linked together by a disulfide bond, and is thought to be involved in liver regeneration. Using a
Hepatocyte growth factor for liver disease
โ Scribed by Hirohito Tsubouchi
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 43 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0270-9139
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In vitro studies have shown hepatocyte growth factor (HGF) to be a potent mitogen for hepatocytes. Direct evidence of a mitogenic role in vivo was sought by inhibiting HGF activity, using continuous administration of neutralizing antibody to rats which had a stimulus for liver regeneration. Alzet os
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