Hepatocellular carcinoma on cirrhosis-free liver in a HCV-infected thalassemic

✍ Scribed by Andrea Mancuso; Paolo Rigano; Disma Renda; Veronica Di Salvo; Caterina Borgna Pignatti; Francesca Guddo; Antonio Buccellato; Nicola Nicoli; Aurelio Maggio

• Book ID: 101434466
• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 217 KB
• Volume: 78
• Category: Article
• ISSN: 0361-8609
• DOI: 10.1002/ajh.20289

✦ Synopsis

of thalassemics due to the development of better chelating drugs will surely make HCC a major problem for thalassemics in future. Nowadays the outcome of HCC can be improved by various treatments, and when HCC develops in absence of cirrhosis, liver surgery can be curative [1,2]. However, early detection of HCC is mandatory. Our experience suggests that US screening should be performed strictly in thalassemia syndromes, particularly when there is either HCV or HBV infection or sustained iron overload.