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Hepatocellular carcinoma arising from non-cirrhotic nonalcoholic steatohepatitis

✍ Scribed by Natsuko Kawada; Kazuho Imanaka; Tsukasa Kawaguchi; Chie Tamai; Ryu Ishihara; Takashi Matsunaga; Kunihito Gotoh; Terumasa Yamada; Yasuhiko Tomita

Publisher: Springer Japan
Year: 2009
Tongue: English
Weight: 369 KB
Volume: 44
Category: Article
ISSN: 0944-1174
DOI: 10.1007/s00535-009-0112-0

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The team of Liu et al. generated endoderm-derived human induced pluripotent stem (iPS) cells from primary hepatocytes. 1 However, they generated human iPS cells by using viral transgenes. 1 Clinical applications of human iPS cells require avoiding viral transgenes. On the other hand, the reprogrammi