Hepatitis C virus RNA in saliva of patients with post-transfusion hepatitis C infection
✍ Scribed by Wang, Jin-Town; Wang, Teh-Hong; Lin, Jaw-Town; Sheu, Jin-Chuan; Lin, Sy-Ming; Chen, Ding-Shinn
- Book ID
- 122956848
- Publisher
- The Lancet
- Year
- 1991
- Tongue
- English
- Weight
- 144 KB
- Volume
- 337
- Category
- Article
- ISSN
- 0140-6736
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## Abstract The prevalence of hepatitis‐C virus (HCV) infection was investigated in a group of children with chronic post‐transfusion hepatitis using a first‐and second‐generation HCV‐antibody ELISA, 2 confirmatory tests (a second‐generation recombinant immunoblot assay and a line immunoas‐say) as
Sera from 103 patients were tested for hepatitis C virus RNA by nested polymerase chain reaction assay. Using primers from the highly conserved 5'-untranslated region, we detected hepatitis C virus RNA in 67 (88.2%) of 76 patients positive for antibody to hepatitis C virus by both second-generation