Hepatitis C virus infection and interferon therapy in patients with Down syndrome
β Scribed by Yoko Miyoshi; Hitoshi Tajiri; Mariko Okaniwa; Sousuke Terasawa; Tomoo Fujisawa; Toshiyuki Iizuka; Keiichi Ozono
- Book ID
- 108971426
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 69 KB
- Volume
- 50
- Category
- Article
- ISSN
- 1328-8067
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π SIMILAR VOLUMES
Of 74 patients who were infected with hepatitis C virus (HCV) and received interferon, 12 (16%) were positive for RNA of GB virus C (GBV-C). RNA of GBV-C was determined in sera from the co-infected patients retrospectively, and the effect of interferon on GBV-C was compared with that on HCV in them.
Sera from 103 patients were tested for hepatitis C virus RNA by nested polymerase chain reaction assay. Using primers from the highly conserved 5'-untranslated region, we detected hepatitis C virus RNA in 67 (88.2%) of 76 patients positive for antibody to hepatitis C virus by both second-generation