✦ LIBER ✦

Hepatitis C virus in the etiology of chronic hepatitis and liver cirrhosis: Possibility of mixed viral infections due to parenteral transmission

✍ Scribed by M. O. Favorov; Dr. H. A. Fields; T. L. Yashina; E. Z. Goldberg; A. K. Yeramishantsev; H. K. Rakchimova; A. N. Burkov; H. S. Margolis; D. K. Lvov

Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 414 KB
Volume: 36
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890360307

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Sera obtained from 381 patients with chronic liver disease from four cities within the USSR were studied for HBV, HDV, and HCV markers of infection. Anti‐HCV activity was detected in 41.2% of non‐A, non‐B cases. The etiological distribution of chronic hepatitis in Moscow and Dushanbe was similar with an approximate 20% prevalence for HBV, HDV, and HCV infections, whereas in Yakatsk 40% of cases were caused by HDV infections. The etiology of disease remained unrecognized in approximately 40% of patients with chronic liver disease in Moscow and Dushanbe and in 15% in Yakutsk. Anti‐HCV activity was detected in 18.8% of patients with chronic HBV infections and in 8.3% of patients with chronic HDV infections. Anti‐HCV activity was detected in 41% of patients without markers of HBV or HDV infections. The reasons for the observed differences in HCV prevalence among patients chronically infected with HDV are discussed.

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