Hepatitis C virus (HCV)-specific CD8+ T cells in patients with recurrent HCV-infection after liver transplantation (OLTx)
β Scribed by C.A. Schirren; N.H. Gruener; M.C. Jung; R. Zachoval; J.T. Gerlach; H. Diepolder; M. Houghton; H.G. Rau; G.R. Pape
- Book ID
- 119527243
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 135 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0168-8278
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Virus-specific CD8+ T cells play a major role in antiviral immune defenses; their significance in the transplant setting, however, is unclear. In the present study, we asked whether hepatitis C virus (HCV)-specific CD8+ T cells were detectable in the presence of an immunosuppressive treatment and wh
## Abstract Hepatitis C virus (HCV) RNA persistence in the liver has been described even after apparent resolution of HCV infection. Because Tβcell reactivity plays a role in recovery from HCV infection, virusβspecific Tβcell responses were investigated in apparently recovered individuals in whom h