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Hepatitis C virus core protein downregulates E-cadherin expression via activation of DNA methyltransferase 1 and 3b

✍ Scribed by Payal Arora; Eun-Ok Kim; Jin Kyu Jung; Kyung Lib Jang

Book ID
116334607
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
399 KB
Volume
261
Category
Article
ISSN
0304-3835

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Both molecular and clinical evidence support a link between HCV infection and insulin resistance. We examined the in vitro interaction between the HCV core protein of genotypes 3a and 1b with the insulin-signaling pathway. We measured the expression levels of insulin receptor substrate 1 (IRS-1), IR