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Hepatitis B virus X protein up-regulates tumor necrosis factor-α expression in cultured mesangial cells via ERKs and NF-κB pathways

✍ Scribed by Lu, Hong-Zhu; Zhou, Jian-Hua


Book ID
123571521
Publisher
Medknow Publications
Year
2013
Tongue
English
Weight
920 KB
Volume
3
Category
Article
ISSN
2221-1691

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The hepatitis B virus X protein up-regul
✍ Enrique Lara-Pezzi; Pedro L. Majano; Marta Gómez-Gonzalo; Carmelo García-Monzón; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 484 KB

Human hepatocytes infected by hepatitis B virus (HBV) produce the proinflammatory cytokine, tumor necrosis factor (TNF-). In this study, we explored the mechanism of induction of TNF- synthesis by HBV. We found that the stable HBV-transfected hepatoma cell line, 2. 2.15, expressed high-molecular-wei