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Hepatitis B virus X protein overcomes oncogenic RAS-induced senescence in human immortalized cells

โœ Scribed by Naoki Oishi; Khurts Shilagardi; Yasunari Nakamoto; Masao Honda; Shuichi Kaneko; Seishi Murakami

Book ID
108583985
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
686 KB
Volume
98
Category
Article
ISSN
1347-9032

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Identification of a protein isolated from senescent human cells that binds to hepatitis B virus X antigen
โœ Bill S. Sun; Xianhua Zhu; Marcy M. Clayton; Jingbo Pan; Mark A. Feitelson ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 430 KB ๐Ÿ‘ 1 views

Hepatitis B virus-encoded X antigen contributes to the development of hepatocellular carcinoma. Given that X antigen functions by binding to other proteins, additional X-binding proteins were sought from an adult human liver cDNA library in a yeast two-hybrid system. The results yielded a clone enco