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Hepatitis B virus variants in patients receiving lamivudine treatment with breakthrough hepatitis evaluated by serial viral loads and full-length viral sequences

✍ Scribed by Chun-Jen Liu; Pei-Jer Chen; Ming-Yang Lai; Jia-Horng Kao; Ding-Shinn Chen

Book ID
111721605
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
146 KB
Volume
34
Category
Article
ISSN
0270-9139

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## Abstract Lamivudine therapy often causes breakthrough of hepatitis B virus (HBV) DNA and breakthrough hepatitis. The aim of this study was to determine the viral factors that relate to HBV‐DNA breakthrough with and without breakthrough hepatitis. Among 82 patients with chronic hepatitis B (CHB)