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Hepatitis B virus reactivation in breast cancer patients undergoing cytotoxic chemotherapy and the role of preemptive lamivudine administration

โœ Scribed by M. S. Dai; P. F. Wu; R. Y. Shyu; J. J. Lu; T. Y. Chao


Book ID
111237277
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
139 KB
Volume
24
Category
Article
ISSN
0106-9543

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Hepatitis B virus (HBV) reactivation has been described in cancer patients who received cytotoxic/immunosuppressive therapy and may result in liver damage of varying degrees of severity. There is no known effective treatment. Lamivudine, a nucleoside analogue, has been found to suppress HBV replicat

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## Abstract Breast cancer is a rapidly increasing problem in many developing countries, and cytotoxic chemotherapy is now an integral part of its management. In several developing countries, the carriage of hepatitis B virus (HBV) in cancer patients may be as high as 12%, and such patients are at r