Hepatitis B virus precore mutants in serum and liver of Southern African Blacks with hepatocellular carcinoma
β Scribed by Anna Kramvis; Michael C Kew; Stanley Bukofzer
- Book ID
- 118567984
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 157 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0168-8278
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π SIMILAR VOLUMES
Sera from 106 southern African blacks with hepatocellular carcinoma and hepatitis B surface antigenemia (HBsAg) were tested for hepatitis B viral DNA (HBV-DNA) activity, HBV-DNA polymerase concentrations, and HBV e antigen (HBeAg) and antibody (anti-HBe) to investigate the state of viral replication
## Abstract Although viral loads are known to influence the development of hepatitis B virusβinduced hepatocellular carcinoma in a number of populations, little information is available in the Black African population. Black African patients with hepatocellular carcinoma differ from those in other
Hepatocellular carcinoma (HCC) is less common and occurs at a much older age in urban than in rural southern African Blacks. These differences may reflect differences in the etiology of the tumor in the two populations. The purpose of this study was to compare the hepatitis B virus (HBV) status of 1