Hepatitis B virus polymerase interferes with interferon-β induction
✍ Scribed by Shiyan Yu; Jieliang Chen; Min Wu; Hui Chen; Zhenghong Yuan
- Book ID
- 116399018
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 52 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1043-4666
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## Abstract The effects of heat, sodium hypochlorite, diethyl ether, and ethyl alcohol on the activity of DNA polymerase (DNA‐P) associated with hepatitis B virsus (HBV) in serum were evaluated. The response of DNA‐P to heating at 60°C for 15, 30, 45, 60, 90, 120, 180, and 240 minutes was studied a
## Abstract Thirty‐nine patients (62 sera) who, after interferon‐α therapy for chronic hepatitis B virus (HBV) infection, were seronegative for HBeAg and HBV‐DNA by dot blot hybridisation, were tested using the polymerase chain reaction (PCR) for residual viraemia. Overall, 59% of the HBsAg‐positiv