Hepatitis B virus (HBV) genotypes/subgenotypes in China: Mutations in core promoter and precore/core and their clinical implications
โ Scribed by Jing Yuan; Boping Zhou; Yasuhito Tanaka; Fuat Kurbanov; Etsuro Orito; Zuojiong Gong; Liumei Xu; Jian Lu; Xiaoling Jiang; Weizhen Lai; Masashi Mizokami
- Book ID
- 116631154
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 252 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1386-6532
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## Abstract Using phylogenetic analysis and pairwise comparison of 670 complete hepatitis B virus (HBV) genomes, we demonstrated that nucleotide divergence greater than 7.5% can be used to separate strains into genotypes AโH. Strains can be separated into subgenotypes when two criteria are met: nuc
## Abstract The association of precore stop codon mutation (A1896), dinucleotide mutation (T1762/A1764) in the basic core promoter of hepatitis B virus (HBV) genome, and genotype of HBV with fulminant or subfulminant hepatitis remains controversial. We studied HBV genotypes as well as mutations in