Serum hepatitis B surface antigen (HBsAg) levels may reflect the immunomodulatory efficacy of pegylated interferon (PEG-IFN). We investigated within a large randomized trial whether quantitative HBsAg levels predict response to PEG-IFN in patients with hepatitis B e antigen (HBeAg)-positive chronic
Hepatitis B virus genotype B results in better immediate, late and sustained responses to peginterferon-alfa in hepatitis-B-e-antigen-positive patients
β Scribed by Chien-Hung Chen; Chuan-Mo Lee; Chao-Hung Hung; Jing-Houng Wang; Tsung-Hui Hu; Chi-Sin Changchien; Sheng-Nan Lu
- Book ID
- 108953844
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 412 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0815-9319
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Bristol-Myers Squibb, Gilead, and Novartis. He is also in the speakers' bureau of Schering-Plough. Dr. Lau is on the speakers' bureau of and received grants from Roche and Novartis. Dr. Piratvisuth advises and is on the speakers' bureau of Roche. He advises Novartis and Schering-Plough and is on th
## Abstract Variation at the ILβ28B locus was recently reported to be a significant predictive factor of viral response to pegylatedβinterferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including ILβ28B polymorphism rs8099917 and v
As there is currently a lack of consensus on the most appropriate dose and duration of peginterferon alfa-2a (PEG-IFNΞ±-2a) therapy in hepatitis B e antigen (HBeAg)-positive patients, the efficacy and safety of either 24 or 48 weeks' duration and 90 ΞΌg/week or 180 ΞΌg/week doses were compared. HBeAg-p