Hepatitis B virus genome variability and disease progression: the impact of pre-core mutants and HBV genotypes
β Scribed by Maria Buti; Francisco Rodriguez-Frias; Rosendo Jardi; Rafael Esteban
- Book ID
- 117769907
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 433 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1386-6532
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The clinical importance of hepatitis B virus (HBV) genome variability has been reported recently. One example is the occurrence of hepatitis B virus pre-core mutants, which arise during spontaneous or interferon-induced seroconversion from HBeAg to anti-HBe and are thought to be selected by immune p
## Abstract The characteristics of hepatitis B virus (HBV) genotype E are not well known because only a few studies have been carried out by complete genome analysis. The aim of this study was to elucidate the distribution of HBV genotypes in Cote d'Ivoire, and to clarify the genotypeβrelated chara
## Abstract The virologic determinants of progressive liver disease associated with hepatitis B virus (HBV) remain unclear. Previous investigations have associated HBV disease with specific mutations but this association may be confounded by HBV genotype, HLA haplotype of the infected individual or