Hepatitis B virus DNA forms in the liver of chronically infected individuals
โ Scribed by Pontisso, P.; Bortolotti, F.; Fattovich, G.; Ruvoletto, M.G.; Realdi, G.; Alberti, A.
- Book ID
- 123436526
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 450 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0168-8278
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## Abstract Hepatitis B virus (HBV) DNA may persist in the liver in the absence of serum HBVโDNA after a selfโlimited acute hepatitis B. This may also occur in patients with chronic hepatitis C virus (HCV) infection but its prevalence and its impact on liver histology is unknown. HBVโDNA was tested
In the present study we have investigated 53 patients with a spectrum of acute and chronic hepatitis B virus (HBV) infection for the presence of leucocyte HBV-DNA with the aid of molecular techniques. HBV-DNA was detected in peripheral blood mononuclear cells of 31 of 45 (69%) of chronic HBsAg carri
## Abstract The patterns of hepatitis B virus DNA (HBVโDNA) expression were studied in 2 sequential liver biopsies from 26 children (18 treated with interferon and 8 controls) with chronic hepatitis B. In the basal biopsy replicative forms of HBVโDNA were detected in all of the samples and integrat