Hepatitis B Virus Core Antigen: Enhancement of Its Production in Escherichia coli, and Interaction of the Core Particles with the Viral Surface Antigen
โ Scribed by Tan, W.S.; Dyson, M.R.; Murray, K.
- Book ID
- 115440352
- Publisher
- Walter de Gruyter GmbH & Co. KG
- Year
- 2003
- Tongue
- English
- Weight
- 304 KB
- Volume
- 384
- Category
- Article
- ISSN
- 1431-6730
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Fusion of peptide epitopes to the core antigen (HBcAg) of hepatitis B virus (HBV) enhances their immunogenicity, both quantitatively and qualitatively. In a number of vaccine-induced mutants of HBV, glycine145 of the surface antigen S polypeptide (HBsAg) has been replaced by arginine, resulting in l
## Abstract The e antigen (HBeAg) of hepatitis B virus (HBV) is a polypeptide of 17โ20,000 daltons closely associated with the core antigen (HBcAg) of Dane particles, from which it is released by a variety of disruptive procedures. HBeAg could be a unique component of HBV core particles or a deriva