Hepatitis B virus code promoter sequence analysis in fulminant adn chronic hepatitis B
β Scribed by LASKUS, T
- Book ID
- 123332797
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 140 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0270-9139
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## Abstract The association of precore stop codon mutation (A1896), dinucleotide mutation (T1762/A1764) in the basic core promoter of hepatitis B virus (HBV) genome, and genotype of HBV with fulminant or subfulminant hepatitis remains controversial. We studied HBV genotypes as well as mutations in
Hepatitis B virus DNA and hepatitis D virus RNA, the most sensitive markers of hepatitis B and hepatitis D virus replication, were sought by molecular hybridization with radioactive probes in serial serum samples from 29 consecutive patients with HBsAg-positive fulminant hepatitis. Nineteen patients
Pre-corekore mutants are frequently observed in patients with fulminant hepatitis. To investigate the extent of molecular characteristics of hepatitis B virus (HBV) genomes implicated in the development of fulminant hepatitis, fulllength HBV genomes were sequenced directly from sera of two patients