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✦   LIBER   ✦

πŸ“

Hepatitis B Virus and Liver Disease

✍ Scribed by Jia-Horng Kao, Ding-Shinn Chen (eds.)


Publisher
Springer Singapore
Year
2018
Tongue
English
Leaves
362
Edition
1
Category
Library

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✦ Synopsis


This book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments as possible cures for HBV infection. The book is a valuable resource for medical students, physicians, and researchers who are interested in managem

ent of patients with chronic HBV infection and investigation of HBV infection.

✦ Table of Contents


Front Matter ....Pages i-xvii
Molecular Virology and Life Cycle (Darren J. Wong, Stephen A. Locarnini)....Pages 1-23
Unmet Needs in Basic Research: In Vitro and In Vivo Models (Kazuaki Chayama, C. Nelson Hayes)....Pages 25-43
Immunopathogenesis of Hepatitis B Virus (HBV) Infection (Fu-Sheng Wang, Ji-Jing Shi)....Pages 45-62
Epidemiology and Natural History of Chronic Hepatitis B Virus Infection (Yael Bogler, Robert J. Wong, Robert G. Gish)....Pages 63-89
Hepatitis B Vaccines (John W. Ward, Pierre Van Damme)....Pages 91-117
Viral Factors Affecting Disease Progression (Hung-Chih Yang)....Pages 119-133
Hepatitis B Virus Genotype and Mutations Related to Clinical Outcome (Masaya Sugiyama, Tadasu Shin-I, Masashi Mizokami)....Pages 135-142
Molecular Carcinogenesis of HBV-Related HCC (Valerie Fako, Xin W. Wang)....Pages 143-162
Non-invasive Assessment of Liver Disease (Henry Lik-Yuen Chan, Vincent Wai-Sun Wong)....Pages 163-179
Chronic HBV Infection: Interferon Therapy and Long-Term Outcomes (Tarik Asselah, Patrick Marcellin)....Pages 181-191
Nucleos(t)ide Therapy and Long-Term Outcomes (Jonggi Choi, Young-Suk Lim)....Pages 193-217
Combination Therapy (Di Wu, Qin Ning)....Pages 219-237
Treatment of HCV, HDV, or HIV Coinfection (Carla S. Coffin, Norah A. Terrault)....Pages 239-262
Management of Chronic Hepatitis B Virus Infection in Children and Pregnant Women (Ming-Wei Lai, Huey-Ling Chen, Mei-Hwei Chang)....Pages 263-296
Occult Hepatitis B Infection (Man-Fung Yuen)....Pages 297-313
Hepatitis B Virus Reactivation and Management of Patients Undergoing Immunosuppression (Prowpanga Udompap, W. Ray Kim)....Pages 315-341
Exploring New Therapies for a Serological Cure of Chronic Hepatitis B (Jau-Hau Horng, Chang-Ru Wu, Pei-Jer Chen)....Pages 343-353
Back Matter ....Pages 355-360

✦ Subjects


Hepatology


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