𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hepatitis B vaccination in infants of mothers infected with human immunodeficiency virus

✍ Scribed by M. P. Arrazola; Dr. J. R. De Juanes; A. J. Aragón; A. Garcia de Codes; J. T. Ramos

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
326 KB
Volume
45
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

A study was conducted to investigate the immunogenicity of a recombinant DNA hepatitis B vaccine in neonates and children of HIV‐infected women. Immunization against hepatitis B consisted of three 10 μg doses of the vaccine administered on a 0‐, 1‐ and 6‐month schedule. The children were followed up for an average of 11 months. Of the 118 HIV‐positive neonates who participated in the study, 95 lost their HIV antibodies during the follow‐up period. Most (94.2%) of the latter who completed the study responded to the vaccine. Of the 23 who remained HIV‐positive, 17 completed the study and 7 produced hepatitis B antibodies. © 1995 Wiley‐Liss, inc.

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