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Hepatitis B transmission from a liver donor who tested negative for hepatitis B surface antigen and positive for hepatitis B core antibody

✍ Scribed by Radomski, John S. ;Moritz, Michael J. ;Armenti, Vincent T. ;Muñoz, Santiago J.

Publisher
Wiley (John Wiley & Sons)
Year
1996
Tongue
English
Weight
135 KB
Volume
2
Category
Article
ISSN
1074-3022

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✦ Synopsis

ne response to the shortage of cadaver organs 0 has been to evaluate donors previously not considered suitable. One group consists of donors who are hepatitis B surface antigen-negative (HBsAg[ -1) and hepatitis B core antibody-positive (HBcAb[+]). We present a case report of an individual receiving an orthotopic liver transplant (OLT) from a HBsAg(-), HBcAb(+) donor with the development of liver failure after transplantation secondary to hepatitis B.

A 63-year-old female with cirrhosis caused by alpha-I-antitrypsin deficiency underwent OLT on November 22, 1993. Her hepatitis B serology results before transplantation were HBsAg(-), HBcAb(-), and HBsAb(-). The donor, a 67-year-old female, had normal transaminase and bilirubin levels but was From the Departments of 'Surge9 and #Medicine, Jefferson

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