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Hepatitis B e antigen predicts delayed reduction of HBV DNA without viral breakthrough with adefovir dipivoxil and lamivudine: A 5-year study of patients with hepatitis B with lamivudine resistance

✍ Scribed by Fusao Ikeda; Nobuyuki Baba; Koichi Takaguchi; Junichi Kubota; Kenji Miyoshi; Shin-ichi Fujioka; Yuki Moritou; Yasuto Takeuchi; Tetsuya Yasunaka; Yasuhiro Miyake; Akinobu Takaki; Yoshiaki Iwasaki; Haruhiko Kobashi; Kazuhide Yamamoto


Book ID
115559021
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
288 KB
Volume
84
Category
Article
ISSN
0146-6615

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This study was undertaken to compare the early antiviral activity and viral kinetic profiles of entecavir (ETV) versus adefovir (ADV) in hepatitis B e antigen positive nucleoside-naΓ―ve adults with chronic hepatitis B (CHB). Sixty-nine nucleoside-naΓ―ve CHB patients with baseline HBV DNA of 10(8) copi